|
5-MeO-DMT Info
The following quote regarding the pharmacological effects of 5-MeO-DMT
snorted alone, and with harmaline or harmine, is excerpted and adapted from p.102 of:
Shamanic Snuffs or Entheogenic Errhines by Jonathan Ott (Entheobotanica, 2001).
5-MeO-DMT--Intranasal Psychonautics [MN] I conducted in all six bioassays (MN-I-MN-VI) by way of modeling the Virola snuffs.
MN-I
With this protocol (MN-I), it was established that 10 mg of [5-MeO-DMT] free-base was the intranasal threshold-dose, evoking a characteristic pharmacodynamic profile for this compound as errhine: first effects at 34 minutes; building to a peak between 3040 minutes; clearly diminishing by 50 minutes; with termination at about 6070 minutes.
MN-II-->MN-V
MN-II-->MN-V dealt with combinations of b-carbolines with [5-MeO-DMT]. The same 10 mg dose was thus combined with 20, 10 and 5 mg (MN-II, MN-III, MN-IV) harmaline hydrochloride dihydrate (harmaline; 14.9/7.5/3.7 mg harmaline free-base; Acros Organics, Geel, Belgie). In each case, I had significant and dramatic potentiation of this threshold-dose of [5-MeO-DMT], irrespective of the diminishing dosage of harmaline--that is, even the minimal dose was appreciably as effective as the maximal in this regard.
MN-V
MN-V was a control-experiment insufflating simply 10 mg harmaline (or 7.5 mg base), which provoked no noticeable effects.
MN-VI
For MN-VI I insufflated 5 mg [5-MeO-DMT] with 5 mg harmine hydrochloride dihydrate (harmine; 3.7 mg harmine free-base; Acros Organics), which gave effects commensurate with MN-I (10 mg [5-MeO-DMT] neat)--both b-carbolines roughly doubling the potency of [5-MeO-DMT].
| Last Modified - Fri, Mar 31, 2006 | Used by Erowid without permission of author |
| [ Back to 5-MeO-DMT Vault ] |
|---|
|
[Plants & Drugs]
[Mind & Spirit]
[Freedom & Law]
[Arts & Sciences]
[Library]
[Search]
[About] (html and design © 1995-2005 Erowid.org. Please ask permission before publicly reproducing.) (Contents © respective copyright holders.) |
|---|